SET 9:131445703-131458679

Forward strand gene: SET nuclear proto-oncogene

Also known as: TAF-I, IGAAD, TAF-IBETA, IPP2A2, 2PP2A, PHAPII, ENSG00000119335

Function: Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves … Source: UniProt

DECIPHER holds 8 sequence variants in this gene, in 8 open-access patients