FBXW11 5:171288553-171433877

Reverse strand gene: F-box and WD repeat domain containing 11

Formerly known as: FBXW1B

Also known as: Fbw11, Hos, BTRC2, BTRCP2, Fbw1b, KIAA0696, ENSG00000072803

Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) … Source: UniProt

DECIPHER holds 2 sequence variants in this gene, in 2 open-access patients