AKT1S1 19:50372295-50381716

Reverse strand gene: AKT1 substrate 1

Also known as: Lobe, MGC2865, PRAS40, ENSG00000204673

Function: Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which … Source: UniProt

DECIPHER holds no open-access sequence variants in this gene