AIF1 6:31582961-31584798

Forward strand gene: allograft inflammatory factor 1

Also known as: IBA1, Em:AF129756.17, AIF-1, IRT-1, ENSG00000204472

Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular … Source: UniProt

DECIPHER holds no open-access sequence variants in this gene