AICDA 12:8754762-8765467

Reverse strand gene: activation induced cytidine deaminase

Also known as: AID, ARP2, CDA2, HIGM2, ENSG00000111732

Function: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several … Source: UniProt

DECIPHER holds no open-access sequence variants in this gene