AGXT2 5:34998206-35048198

Reverse strand gene: alanine--glyoxylate aminotransferase 2

Also known as: AGT2, ENSG00000113492

Function: Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure. Source: UniProt

DECIPHER holds no open-access sequence variants in this gene