AGO2 8:141541264-141645718

Reverse strand gene: argonaute RISC catalytic component 2

Formerly known as: CASC7, EIF2C2

Also known as: LINC00980, Q10, hAGO2, ENSG00000123908

Function: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that… Source: UniProt

DECIPHER holds no open-access sequence variants in this gene