ADAMTS4 1:161154098-161168846

Reverse strand gene: ADAM metallopeptidase with thrombospondin type 1 motif 4

Also known as: ADMP-1, ADAMTS-2, KIAA0688, ENSG00000158859

Function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at theā€¦ Source: UniProt

DECIPHER holds no open-access sequence variants in this gene