ACAN 15:89346674-89418585

Forward strand gene: aggrecan

Formerly known as: AGC1, CSPG1, MSK16

Also known as: CSPGCP, ENSG00000157766

Function: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. Source: UniProt

DECIPHER holds 7 sequence variants in this gene, in 7 open-access patients