ABCB4 7:87031013-87109751

Reverse strand gene: ATP binding cassette subfamily B member 4

Formerly known as: MDR3, PGY3

Also known as: GBD1, PFIC-3, MDR2, ENSG00000005471

Function: Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates specifically phosphatidylcholine (PC) from the inner to the outer leaflet of the canalicular membrane bilayer into the … Source: UniProt

DECIPHER holds 1 sequence variants in this gene, in 1 open-access patients