AAK1 2:69688532-69901481

Reverse strand gene: AP2 associated kinase 1

Also known as: DKFZp686K16132, KIAA1048, ENSG00000115977

Function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels… Source: UniProt

DECIPHER holds no open-access sequence variants in this gene